Study objective was to assess the impact of complementary feeding bottles given at maternity hospital and/or over the first month after discharge from the maternity ward on cow’s milk allergy (CMA) risk in breastfed infants…
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Single-cell RNA sequencing (scRNA-seq) revolutionized our understanding of disease biology. The promise it presents to also transform translational research requires highly standardized and robust software workflows. Here, we present the toolkit Besca, which streamlines …
Individual diet components and specific dietary regimens have been shown to impact the gut microbiome.In this study, we explored the contribution of long-term diet by searching for dietary patterns that would best associate with the gut microbiome in a population-based cohort.
New Caledonia is a Pacific island of 270,000 inhabitants with mixed ethnicities, including Polynesians (10.2%), people from European ancestry (27.2%), and Melanesians (39.1%),. This study aimed at determining the prevalence of gout and hyperuricemia in the general population and the various ethnicities of New Caledonia.
Lipopolysaccharide (LPS) and monophosphoryl lipid A (MPLA) induce, overall, similar transcriptional profiles in healthy individuals, although LPS has been shown to more potently induce pro-inflammatory cytokines. We explore herein whether MPLA could be considered as a synthetic replacement of LPS in immune functional assays to study anergy of immune cells in septic patients.
We hypothesize that chondrocytes from the deepest articular cartilage layer are pivotal in maintaining cartilage integrity and that the modification of their prehypertrophic phenotype to a hypertrophic phenotype will drive cartilage degradation in osteoarthritis.
Environmental exposure chambers (EECs) have been used extensively to study allergic rhinoconjunctivitis. Few studies have been published using EECs in conjunctivitis only, and none have used conjunctival allergen challenge as a selection criterion…
Les technologies numériques permettent de faciliter le recueil d’information de santé et de nutrition par les participants aux études cliniques. Cependant, l’appétence à ces technologies est généralement évaluée en population générale, auprès de patients…
Angiogenesis is a key process in tumor growth and metastasis, as adequate vasculature and blood supply ensures tumor growth and development [1]. In normal tissues, blood vessel growth is usually kept to a minimum, and angiogenesis is regulated by a balance…
The Pneumo-Quest self-questionnaire was developed to standardize the practice of recollection when welcoming a new patient. It consists of 82 main questions and 34 subsidiary questions to be completed at home by the patients before their first visit to a pulmonologist. This evaluation was carried out on the basis of 137 returned questionnaires.
